Browsing by Author "Mpairwe, Harriet"

Now showing items 1-9 of 9

    • Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results 

      Mpairwe, Harriet; Webb, Emily L; Muhangi, Lawrence; Ndibazza, Juliet; Akishule, Denise; Nampijja, Margaret; Ngom-wegi, Sophy; Tumusime, Josephine; Jones, Frances M; Fitzsimmons, Colin; Dunne, David W.; Muwanga, Moses; Rodrigues, Laura C.; Elliott, Alison M (John Wiley & Sons A/S, 2011)
      Background: Allergy is commoner in developed than in developing countries. Chronic worm infections show inverse associations with allergy, and prenatal exposures may be critical to allergy risk. Objective: To determine ...

    • Associations Between Maternal Helminth and Malaria Infections in Pregnancy and Clinical Malaria in the Offspring: A Birth Cohort in Entebbe, Uganda 

      Ndibazza, Juliet; Webb, Emily L; Lule, Swaib; Mpairwe, Harriet; Akello, Miriam; Oduru, Gloria; Kizza, Moses; Akurut, Helen; Muhangi, Lawrence; Magnussen, Pascal; Vennervald, Birgitte J.; Elliott, Alison M (Oxford University Press on behalf of the Infectious Diseases Society of America, 2013)
      Helminth and malaria coinfections are common in the tropics. We investigated the hypothesis that prenatal exposure to these parasites might influence susceptibility to malaria in childhood. Methods. In a birth cohort of ...

    • A Description of Congenital Anomalies Among Infants in Entebbe, Uganda 

      Ndibazza, Juliet; Lule, Swaib; Nampijja, Margaret; Mpairwe, Harriet; Oduru, Gloria; Kiggundu, Molly; Akello, Miriam; Muhangi, Lawrence; Elliott, Alison M (Wiley-Liss, Inc., 2011)
      Background: Data on congenital anomalies from developing countries of the sub-Saharan region are scarce. However, it is important to have comprehensive and reliable data on the description and prevalence of congenital ...

    • Effect of Single-Dose Anthelmintic Treatment During Pregnancy on an Infant’s Response to Immunisation and on Susceptibility to Infectious Diseases in Infancy: a Randomised, Double-Blind, Placebo-Controlled Trial 

      Ndibazza, Juliet; Maw, Patrice A.; Webb, Emily L.; Kizito, Dennison; Namatovu, Alice; Kyosiimire-Lugemwa, Jacqueline; Nanteza, Bridget; Nampijja, Margaret; Muhangi, Lawrence; Woodburn, Patrick W.; Akurut, Hellen; Mpairwe, Harriet; Akello, Miriam; Lyadda, Nancy; Bukusuba, Joseph; Kihembo, Macklyn; Kizza, Moses; Kizindo, Robert; Nabulime, Juliet; Ameke, Christine; Namujju, Proscovia B.; Tweyongyere, Robert; Muwanga, Moses; Whitworth, James A. G.; Elliot, Alison M. (2011)
      Helminth infections aff ect the human immune response. We investigated whether prenatal exposure to and treatment of maternal helminth infections aff ects development of an infant’s immune response toimmunisations and ...

    • Impact of Anthelminthic Treatment in Pregnancy and Childhood on Immunisations, Infections and Eczema in Childhood: A Randomised Controlled Trial 

      Ndibazza, Juliet; Mpairwe, Harriet; Webb, Emily L.; Mawa, Patrice A.; Nampijja, Margaret; Muhang, Lawrence; Kihembo, Macklyn; Lule, Swaib A.; Rutebarika, Diana; Apule, Barbara; Akello, Florence; Akurut, Hellen; Oduru, Gloria; Naniima, Peter; Kizito, Dennison; Kizza, Moses; Kizindo, Robert; Tweyongere, Robert; Alcock, Katherine J.; Muwanga, Moses; Elliott, Alison M. (Uganda Martyrs University, 2012)
      Background: Helminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the hypothesis that anthelminthic treatment in pregnancy and early ...

    • Maternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Uganda 

      Muhangi, Lawrence; Lule, Swaib; Mpairwe, Harriet (Public Health Nutrition, 2013)
      Objective: To assess the associations between maternal HIV infection and growth outcomes of HIV-exposed but uninfected infants and to identify other predictors for poor growth among this population. Design: Within a trial ...

    • Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda 

      Mpairwe, Harriet; Ndibazza, Juliet; Webb, Emily L; Nampijja, Margaret; Muhangi, Lawrence; Apule, Barbara; Lule, Swaib; Akurut, Helen; Kizito, Dennison; Kakande, Mohammed; Jones, Frances M; Fitzsimmons, Colin M.; Muwanga, Moses; Rodrigues, Laura C.; Dunne, David W; Elliott, Alison M (Pediatric Allergy and Immunology, 2014)
      Background: Worms may protect against allergy. Early-life worm exposure may be critical, but this has not been fully investigated. Objectives: To investigate whether worms in pregnancy and in early childhood are associated ...

    • Skin Prick Test Reactivity to Common Allergens Among Women in Entebbe, Uganda 

      Mpairwe, Harriet; Muhangi, Lawrence; Ndibazza, Juliet; Tumusiime, Josephine; Muwanga, Moses; Laura, Rodrigues C.; Alison, Elliott M. (2008)
      The objectives of this study were to estimate the prevalence of atopic sensitization,and to identify common aeroallergens associated with atopic sensitization among women inEntebbe, Uganda, and to determine risk factors ...

    • Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child? 

      Elliott, Alison M; Ndibazza, Juliet; Mpairwe, Harriet; Muhangi, Lawrence; Webb, Emily L; Kizito, Dennison; Mawa, Patrice A; Tweyongyere, Robert; Muwanga, Moses (Cambridge University Press, 2011)
      In 1994 and 2002, respectively, theWorld Health Organisation proposed that treatment for hookworm and schistosomiasis could be provided during pregnancy. It was hoped that this might have benefits for maternal anaemia, ...