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The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood [ISRCTN32849447]
(Society for Clinical Trials, 2007)
Helminths have profound effects on the immune response, allowing long-term survival of parasites with minimal damage to the host. Some of these effects “spill-over”, altering responses to non-helminth antigens or allergens. ...
Effects of Maternal and Infant Co-infections, and of Maternal Immunization, on the Infant Response to BCG and Tetanus Immunization
Some vaccines show poor efficacy in tropical countries. Within a birth cohort in Uganda, we investigatedfactors that might influence responses to BCG and tetanus immunisation. Whole blood assay responsesto crude culture ...