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Associations Between Maternal Helminth and Malaria Infections in Pregnancy and Clinical Malaria in the Offspring: A Birth Cohort in Entebbe, Uganda

Ndibazza, Juliet; Webb, Emily L; Lule, Swaib; Mpairwe, Harriet; Akello, Miriam; Oduru, Gloria; Kizza, Moses; Akurut, Helen; Muhangi, Lawrence; Magnussen, Pascal; Vennervald, Birgitte J.; Elliott, Alison M (Oxford University Press on behalf of the Infectious Diseases Society of America, 2013)

Helminth and malaria coinfections are common in the tropics. We investigated the hypothesis that prenatal exposure to these parasites might influence susceptibility to malaria in childhood. Methods. In a birth cohort of ...

Assessing the external validity of a randomized controlled trial of anthelminthics in mothers and their children in Entebbe, Uganda

Millard, James D; Muhangi, Lawrence; Sewankambo, Moses; Ndibazza, Juliet; Elliott, Alison M; Webb, Emily L (BioMed Central, 2014)

The ‘external validity’ of randomized controlled trials is an important measure of quality, but is often not formally assessed. Trials concerning mass drug administration for helminth control are likely to guide public health ...

Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child?

Elliott, Alison M; Ndibazza, Juliet; Mpairwe, Harriet; Muhangi, Lawrence; Webb, Emily L; Kizito, Dennison; Mawa, Patrice A; Tweyongyere, Robert; Muwanga, Moses (Cambridge University Press, 2011)

In 1994 and 2002, respectively, theWorld Health Organisation proposed that treatment for hookworm and schistosomiasis could be provided during pregnancy. It was hoped that this might have benefits for maternal anaemia, ...

Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results

Mpairwe, Harriet; Webb, Emily L; Muhangi, Lawrence; Ndibazza, Juliet; Akishule, Denise; Nampijja, Margaret; Ngom-wegi, Sophy; Tumusime, Josephine; Jones, Frances M; Fitzsimmons, Colin; Dunne, David W.; Muwanga, Moses; Rodrigues, Laura C.; Elliott, Alison M (John Wiley & Sons A/S, 2011)

Background: Allergy is commoner in developed than in developing countries. Chronic worm infections show inverse associations with allergy, and prenatal exposures may be critical to allergy risk. Objective: To determine ...

Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda

Mpairwe, Harriet; Ndibazza, Juliet; Webb, Emily L; Nampijja, Margaret; Muhangi, Lawrence; Apule, Barbara; Lule, Swaib; Akurut, Helen; Kizito, Dennison; Kakande, Mohammed; Jones, Frances M; Fitzsimmons, Colin M.; Muwanga, Moses; Rodrigues, Laura C.; Dunne, David W; Elliott, Alison M (Pediatric Allergy and Immunology, 2014)

Background: Worms may protect against allergy. Early-life worm exposure may be critical, but this has not been fully investigated. Objectives: To investigate whether worms in pregnancy and in early childhood are associated ...

Parasite infection is associated with Kaposi’s sarcoma associated herpesvirus (KSHV) in Ugandan women

Wakeham, Katie; Webb, Emily L; Sebina, Ismail; Muhangi, Lawrence; Miley, Wendell; Johnson, W Thomas; Ndibazza, Juliet; Elliott, Alison M; Whitby, Denise; Newton, Robert (BioMed Central, 2011)

Background: Immune modulation by parasites may influence susceptibility to bacteria and viruses. We examined the association between current parasite infections, HIV and syphilis (measured in blood or stool samples ...