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Risk Factors for Helminth, Malaria, and HIV Infection in Pregnancy in Entebbe, Uganda
(Uganda Martyrs University, 2009)
factors for infections informs planning of interventions and analysis of the impact of infections on health outcomes.To describe risk factors for helminths, malaria and HIV in pregnant Ugandan women before intervention in ...
Effect of Single-Dose Anthelmintic Treatment During Pregnancy on an Infant’s Response to Immunisation and on Susceptibility to Infectious Diseases in Infancy: a Randomised, Double-Blind, Placebo-Controlled Trial
(2011)
Helminth infections aff ect the human immune response. We investigated whether prenatal exposure to and treatment of maternal helminth infections aff ects development of an infant’s immune response toimmunisations and ...
Skin Prick Test Reactivity to Common Allergens Among Women in Entebbe, Uganda
(2008)
The objectives of this study were to estimate the prevalence of atopic sensitization,and to identify common aeroallergens associated with atopic sensitization among women inEntebbe, Uganda, and to determine risk factors ...
The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood [ISRCTN32849447]
(Society for Clinical Trials, 2007)
Helminths have profound effects on the immune response, allowing long-term survival of parasites with minimal damage to the host. Some of these effects “spill-over”, altering responses to non-helminth antigens or allergens. ...
Associations Between Maternal Helminth and Malaria Infections in Pregnancy and Clinical Malaria in the Offspring: A Birth Cohort in Entebbe, Uganda
(Oxford University Press on behalf of the Infectious Diseases Society of America, 2013)
Helminth and malaria coinfections are common in the tropics. We investigated the hypothesis
that prenatal exposure to these parasites might influence susceptibility to malaria in childhood.
Methods. In a birth cohort of ...
Parasite infection is associated with Kaposi’s sarcoma associated herpesvirus (KSHV) in Ugandan women
(BioMed Central, 2011)
Background: Immune modulation by parasites may influence susceptibility to bacteria and viruses. We examined
the association between current parasite infections, HIV and syphilis (measured in blood or stool samples ...
Assessing the external validity of a randomized controlled trial of anthelminthics in mothers and their children in Entebbe, Uganda
(BioMed Central, 2014)
The ‘external validity’ of randomized controlled trials is an important measure of quality, but is often
not formally assessed. Trials concerning mass drug administration for helminth control are likely to guide public
health ...
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results
(John Wiley & Sons A/S, 2011)
Background: Allergy is commoner in developed than in developing countries. Chronic worm infections show inverse associations with allergy, and prenatal exposures may be critical to allergy risk.
Objective: To determine ...
Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda
(Pediatric Allergy and Immunology, 2014)
Background: Worms may protect against allergy. Early-life worm exposure may be critical, but this has not been fully investigated.
Objectives: To investigate whether worms in pregnancy and in early childhood are associated ...
Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child?
(Cambridge University Press, 2011)
In 1994 and 2002, respectively, theWorld Health Organisation proposed that treatment for hookworm and schistosomiasis could be provided during pregnancy. It was hoped that this might have benefits for maternal anaemia, ...