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Assessment of Second-Line Antiretroviral Regimens for HIV Therapy in Africa
(Massachusetts Medical Society., 2014-07-17)
Background
The efficacy and toxic effects of nucleoside reverse-transcriptase inhibitors (NRTIs) are uncertain when these agents are used with a protease inhibitor in second-line therapy for human immunodeficiency virus ...
Lopinavir Plus Nucleoside Reverse-transcriptase Inhibitors, Lopinavir Plus Raltegravir, or Lopinavir Monotherapy for Second-line Treatment of HIV (EARNEST): 144-week Follow-up Results From a Randomised Controlled Trial
(Elsevier, 2018-01)
Background Millions of HIV-infected people worldwide receive antiretroviral therapy (ART) in programmes using WHO-recommended standardised regimens. Recent WHO guidelines recommend a boosted protease inhibitor plus raltegravir ...
Neurocognitive Function at the First-Line Failure and on the Second-Line Antiretroviral Therapy in Africa
(Wolters Kluwer Health, Inc., 2016-04-15)
Objective: To assess neurocognitive function at the first-line antiretroviral therapy failure and change on the second-line therapy.
Design: Randomized controlled trial was conducted in 5 sub-Saharan African countries.
Methods: ...