Browsing by Author "Mutesa L."

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Indoor Air Pollution as a Risk Factor for Fatal Anthracosis and Copd in Sub-Saharan Africa–The Case of an Unidentified Rwandan Male of About 50 Years
(RBC / Rwanda Health Communication Centre, P.O.Box 4586 / Kigali Rwanda., 2016) Blanke-Roeser C; Mushumba H; Sperhake J; Heinemann A; Kyamanywa Patrick; Nyamwasa D; Hakizimana F.X; Mutesa L.; Püschel K.
Background: The deposition of particles of coal dust into the lung tissue, particularly due to high exhaust pollution levels in large cities, smoking, or in the coal mining sector, is generally considered as less harmful than the deposition of other kinds of dust that lead to unspecified clinical pictures of the lung tissue (e.g. asbestosis, silicosis, silicatosis). However, anthracosis, a more or less intensive deposition of coal dust into the pulmonary interstitium and lymphatic system connected with a blackish pigmentation is a common macroscopic and microscopic finding especially in cities and greatly contributes to the development of chronic obstructive lung disease (COPD). The present case report aims at highlighting the high relevance of indoor pollution to the development of COPD and other lung diseases. Methods: We review a case of a 50-year-old Rwandan male autopsied at the Kacyiru Police Hospital as part of an inter-disciplinary Forensic Summer School with the theme” A holistic approach towards a safer society” in the Conference held in Kigali-Rwanda from 24th -27th August 2015. Results: The autopsy revealed severe chronic anthracosis, COPD, pulmonary firosis, emphysema; and a diagnosis of pulmonary insufficiency was made as the cause of death. Conclusion: Indoor air pollution, particularly through the burning of biomass and coal in closed rooms, is a relevant risk factor for the development of pulmonary diseases such as anthracosis and COPD. Mainly affected are regions in developing and emerging countries, especially in the countryside. Therefore, the reduction of the concentration of pollutants inside closed rooms is the most important aim, either by using more effective technical devices or by improving ventilation in these rooms. These objectives should be pursued by educational and policy measures.
Prune-Belly Syndrome: A Case Report from Rwanda
(The College of Surgeons of East, Central and Southern Africa (COSECSA), 2012-07) Ngendahayo E; Kyamanywa Patrick; Mutesa L.; Gashegu J
Background: Prune-Belly syndrome, Eagle-Barret syndrome and triad syndrome, all refer to congenital anomalies involving abdominal musculature, urinary tract and testicles. The syndrome consists of a triad of abdominal muscle aplasia, massive ureteral and bladder dilatation and cryptorchidism. Kidneys are often affected by secondary hydronephrosis or by polycystic dysplasia. The full manifestation of the syndrome occurs almost exclusively in boys. Available reports on the epidemiology and outcome show a high perinatal mortality due to related prematurity and associated pulmonary complications. The management of a prune-belly patient has been controversial. However nowadays, the tendency is to assist primarily prune – belly neonates in respiratory failure, and to limit radical urologic interventions. Case Report: We report hereby a full term prune-belly neonate who succumbed from this condition before being adequately investigated. Our purpose is to call clinicians’ attention to early recognition, investigation and management of the syndrome. Even though infants with a full-blown syndrome have a poor prognosis for long term survival, all patients need careful evaluation and individualized management according to the spectrum of the syndrome. In this paper, the morphogenesis and the developmental biology of the abdominal wall will be also recalled, and literature reviewed.