Interventions to Reduce Pedestrian Road Traffic Injuries: A Systematic Review of Randomized Controlled Trials, Cluster Randomized Controlled Trials, Interrupted Time-series, and Controlled Before-after Studies

dc.contributor.authorNamatovu, Stellah
dc.contributor.authorBalugaba, Bonny E
dc.contributor.authorMuni, Kennedy
dc.contributor.authorNingwa, Albert
dc.contributor.authorNsabagwa, Linda
dc.contributor.authorOporia, Fredrick
dc.contributor.authorKiconco, Arthur
dc.contributor.authorKyamanywa, Patrick
dc.contributor.authorMutto, Milton
dc.contributor.authorOsuret, Jimmy
dc.contributor.authorRehfuess, Evan A
dc.contributor.authorBurns, Jacob
dc.contributor.authorKobusingye, Olive
dc.date.accessioned2022-04-28T08:41:41Z
dc.date.available2022-04-28T08:41:41Z
dc.date.issued2022
dc.description.abstractBackground Road traffic injuries are among the top ten causes of death globally, with the highest burden in low and middle-income countries, where over a third of deaths occur among pedestrians and cyclists. Several interventions to mitigate the burden among pedestrians have been widely implemented, however, the effectiveness has not been systematically examined. Objectives To assess the effectiveness of interventions to reduce road traffic crashes, injuries, hospitalizations and deaths among pedestrians. Methods We considered studies that evaluated interventions to reduce road traffic crashes, injuries, hospitalizations and/or deaths among pedestrians. We considered randomized controlled trials, interrupted time-series studies, and controlled before-after studies. We searched MEDLINE, EMBASE, Web of Science, WHO Global Health Index, Health Evidence, Transport Research International Documentation and ClinicalTrials.gov through 31 August 2020, and the reference lists of all included studies. Two reviewers independently screened titles and abstracts and full texts, extracted data and assessed the risk of bias. We summarized findings narratively with text and tables. Results A total of 69123 unique records were identified through the searches, with 26 of these meeting our eligibility criteria. All except two of these were conducted in high-income countries and most were from urban settings. The majority of studies observed either a clear effect favoring the intervention or an unclear effect potentially favoring the intervention and these included: changes to the road environment (19/27); changes to legislation and enforcement (12/12); and road user behavior/education combined with either changes to the road environment (3/3) or with legislation and enforcement (1/1). A small number of studies observed either a null effect or an effect favoring the control. Conclusions Although the highest burden of road traffic injuries exists in LMICs, very few studies have examined the effectiveness of available interventions in these settings. Studies indicate that road environment, legislation and enforcement interventions alone produce positive effects on pedestrian safety. In combination with or with road user behavior/education interventions they are particularly effective in improving pedestrian safety.en_US
dc.identifier.citationNamatovu, S., Balugaba, B.E., Muni, K., Ningwa, A., Nsabagwa, L., Oporia, F., Kiconco, A., Kyamanywa, P., Mutto, M., Osuret, J. and Rehfuess, E.A. (2022). Interventions to reduce pedestrian road traffic injuries: A systematic review of randomized controlled trials, cluster randomized controlled trials, interrupted time-series, and controlled before-after studies. PloS one, 17(1), p.e0262681.en_US
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/20.500.12280/2988
dc.language.isoenen_US
dc.publisherPublic Library Science, 1160 Battery Street, Ste 100, San Francisco, Usa, Ca, 94111en_US
dc.relation.ispartofseriesPloS one;17(1)
dc.subjectRoadsen_US
dc.subjectTraffic safetyen_US
dc.subjectSchoolsen_US
dc.subjectMedical risk factorsen_US
dc.subjectSystematic reviewsen_US
dc.subjectDeveloping countriesen_US
dc.subjectPreventive medicineen_US
dc.titleInterventions to Reduce Pedestrian Road Traffic Injuries: A Systematic Review of Randomized Controlled Trials, Cluster Randomized Controlled Trials, Interrupted Time-series, and Controlled Before-after Studiesen_US
dc.typeArticleen_US

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