Nodding Syndrome (NS) in Northern Uganda: A Probable Metabolic Disorder

dc.contributor.authorKitara, Lagoro David
dc.contributor.authorMwaka, Amos Deogratius
dc.contributor.authorAnywar, Arony Denis
dc.contributor.authorUwonda, Gilbert
dc.contributor.authorAbwang, Bernard
dc.contributor.authorKigonya, Edward
dc.date.accessioned2021-04-28T08:49:25Z
dc.date.available2021-04-28T08:49:25Z
dc.date.issued2013-07-04
dc.description.abstractAims: To conduct an epidemiological study to establish the association between malnutrition, metabolic disorder and Onchocerciasis to Nodding Syndrome (NS) in Northern Uganda. Study Design: Case-control study design. Place and Duration of Study: Odek and Atiak sub counties in Gulu and Amuru districts between 10th to 20th June 2012. Methodology: We recruited consecutively 101 children with probable NS in the 2 sub counties in Gulu and Amuru districts. Controls were from the same population but without symptoms of NS and were matched by age, sex and residents. History and physical examinations were conducted; anthropometry, blood samples and skin snips were obtained from cases and controls. Researchers were pediatricians, psychiatrists, nurses, laboratory scientists and epidemiologists. The research proposal was approved by the Ministry of Health and the IRB of Gulu University. Results: There was a statistically significant association between NS with malnutrition (t=0.142; p=0.044), Onchocerciasis (Χ 2 = 152.74, p<0.001; OR 7.025 95% CI 3.891, 12.682) and High Anion Gap (Χ2=146.752, p<0.001; OR 6.313 95%CI 4.027, 9.895). Conclusion: Nodding syndrome is associated with metabolic disorder in young children who are malnourished and infected with Onchocerciasis.en_US
dc.identifier.citationKitara, D.L., Mwaka, A.D., Anywar, D.A., Uwonda, G., Abwang, B. and Kigonya, E., 2013. Nodding Syndrome (NS) in Northern Uganda: A probable metabolic disorder. Journal of Advances in Medicine and Medical Research, pp.2054-2068.en_US
dc.identifier.issn2456-8899
dc.identifier.urihttp://hdl.handle.net/20.500.12280/2763
dc.language.isoenen_US
dc.publisherJournal of Advances in Medicine and Medical Researchen_US
dc.relation.ispartofseriesJournal of Advances in Medicine and Medical Research;
dc.subjectNodding syndromeen_US
dc.subjectOnchocerciasisen_US
dc.subjectMalnutritionen_US
dc.subjectMetabolic disorderen_US
dc.subjectGuluen_US
dc.subjectNorthern Ugandaen_US
dc.titleNodding Syndrome (NS) in Northern Uganda: A Probable Metabolic Disorderen_US
dc.typeArticleen_US

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