Risk Factors for Helminth, Malaria, and HIV Infection in Pregnancy in Entebbe, Uganda

dc.contributor.authorNdibazza, Juliet
dc.contributor.authorBazanya, Proscovia Namujju
dc.contributor.authorKizza, Moses
dc.contributor.authorAmeke, Christine
dc.contributor.authorOmoding, Nicolas Emojong
dc.contributor.authorBooth, Mark
dc.contributor.authorElliott, Alison Mary
dc.contributor.authorWoodburn, Patrick William
dc.contributor.authorMuhangi, Lawrence
dc.contributor.authorHillier, Stephen
dc.date.accessioned2019-02-14T11:33:39Z
dc.date.available2019-02-14T11:33:39Z
dc.date.issued2009
dc.description.abstractfactors for infections informs planning of interventions and analysis of the impact of infections on health outcomes.To describe risk factors for helminths, malaria and HIV in pregnant Ugandan women before intervention in a trial of de-worming in pregnancy. The trial recruited 2,507 pregnant women between April 2003 and November 2005. Participants were interviewed and blood and stool samples obtained; location of residence at enrolment was mapped. Demographic, socioeconomic, behavioral and other risk factors were modelled using logistic regression. Results: There was a high prevalence of helminth, malaria and HIV infection, as previously reported. All helminths and malaria parasitemia were more common in younger women, and education was protective against every infection. Place of birth and/or tribe affected all helminths in a pattern consistent with the geographical distribution of helminth infections in Uganda. Four different geohelminths (hookworm, Trichuris, Ascaris and Trichostrongylus) showed a downwards trend in prevalence during the enrolment period. There was a negative association between hookworm and HIV, and between hookworm and low CD4 count among HIV-positive women. Locally, high prevalence of schistosomiasis and HIV occurred in lakeshore communities. Conclusions: Interventions for helminths, malaria and HIV need to target young women both in and out of school. Antenatal interventions for malaria and HIV infection must continue to be promoted. Women originating from a high risk area for a helminth infection remain at high risk after migration to a lower-risk area, and vice versa, but overall, geohelminths seem to be becoming less common in this population. High risk populations, such as fishing communities, require directed effort against schistosomiasis and HIV infection.en_US
dc.identifier.citationNdibazza, J. et al. (2009). Risk Factors for Helminth, Malaria, and HIV Infection in Pregnancy in Entebbe, Uganda. Uganda Martyrs University, Nkozi: Uganda Martyrs University.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12280/1361
dc.language.isoenen_US
dc.publisherUganda Martyrs Universityen_US
dc.subjectRisk Factorsen_US
dc.subjectHelminthen_US
dc.subjectMalaria & HIV Infectionen_US
dc.subjectPregnancyen_US
dc.subjectEntebbe, Ugandaen_US
dc.titleRisk Factors for Helminth, Malaria, and HIV Infection in Pregnancy in Entebbe, Ugandaen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Ndibazza_HSCIE_ARTICLE_2009_Risk Factors.pdf
Size:
220.78 KB
Format:
Adobe Portable Document Format
Description:

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: