Browsing by Author "Petrara, Raffaella Maria"

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    Viral Load Detection Using Dried Blood Spots in a Cohort of HIV-1- Infected Children in Uganda: Correlations with Clinical and Immunological Criteria for Treatment Failure
    (AMER SOC MICROBIOLOGY , 1752 N ST NW, WASHINGTON, USA, DC, 20036-2904, 2014-07) Costenaro, Paola; Lundin, Rebecca; Petrara, Raffaella Maria; Penazzato, Martina; Massavon, William; Kizito, Susan; Nabachwa, Monica Sandra; Musoke, Nannyonga Maria; Namisi, Charles; Morelli, Erika; Bilardi, Davide; Mazza, Antonio; Zanchetta, Marisa; Giaquinto, Carlo; Rossi, De Anita
    Correlations between clinical/immunological treatment failure and viral load (VL) detected by dried blood spot (DBS) sampling were explored in HIV-1-infected children in Uganda. Of 104 children on combined antiretroviral treatment (cART), 12.5% experienced clinical and/or immunological failure, while 28.8%, 44.2%, and 26.9% had VLs of <1,000, 1,000 to 5,000, and >5,000 copies/ml, respectively. Clinical/immunological failure poorly predicted virological failure.